In atherosclerosis, activated T lymphocytes recruited to the wound site detect LDL as antigen and produce pro-inflammatory molecules including IFN-γ and tumor necrosis factor (TNF) which leads to the induction of CXCL9, CXCL10, and CXCL11 expression by the cells of the region, leading to selective homing of Th1 cells expressing CXCR3 (Szentes et al., 2018). This evidence concerns the gene TNF and atherosclerosis.