Consistently, UBAP2L depletion leads to an enrichment of G2/Mitotic (G2/M) population in HeLa cells (Maeda et al., 2016), in ZR-75-30 and in T-47D breast cancer cells (He et al., 2018) and in DU145 prostate cancer cells (Li and Huang, 2014) pointing to an important role of UBAP2L as a cell cycle regulator. Here, UBAP2L is linked to Familial prostate cancer.