In qPCR experiments, BRD4 mRNA and MYC mRNA were detected in primary CML cells, KU812, K562 (Figure S1B,C), highly purified CD34+/CD38− CML LSC, and CD34+/CD38+ CML progenitors (Figure 1C). Here, MYC is linked to chronic myelogenous leukemia, BCR-ABL1 positive.