IL18 and breast cancer: In contrast, the mutant allele A had a positive association (OR, 5.03) suggesting an etiological impact; therefore, women who carry allele A of –607 may be more susceptible to BC than women who have allele C. However, the results of some studies were mixed; in a study involving 72 BC patients and 93 control women, Fathi Maroufi et al. [17] discovered that the IL18 -607A/C polymorphism was not linked to BC in an Iranian population sample.