For example, 3-deazaadenosine inhibits METTL3/METTL14 [277], CA4 (carbonic anhydrase member) induces WTAP degradation and suppresses colorectal cancer proliferation [278], and R-2-hydroxyglutarate (R-2HG) delays leukemia progression via inhibition of FTO [237]. Here, METTL14 is linked to colorectal cancer.