By querying TCGA data sets from a variety of cancer types, we found that Smyca high expression correlated with poor overall survival and disease-free survival of several cancer types, including kidney clear cell carcinoma, lower grade glioma, adrenocortical cancer and mesothelioma (Additional file 1: Fig. S1A, B). The gene discussed is MIR23AHG; the disease is clear cell renal carcinoma.