According to the multivariate analysis (Table 3), after adjusting for sex, BMI, ECOG PS score, Child–Pugh score, baseline metastasis, CRP, and NLR, the OS of patients with sarcopenia was worse than that of patients with no sarcopenia (HR, 5.39; 95% CI, 1.74–16.74; p = 0.004); however, no significant difference was found in PFS between patients with sarcopenia and no sarcopenia (HR, 1.48; 95% CI, 0.82–2.67; p = 0.195). This evidence concerns the gene CRP and sarcopenia.