CD4 and neoplasm: CD8 + T, CD4 + T, and NK cell infiltration levels in tumor tissue prior to nCRT were 3.5% ± 3.6%, 1.4% ± 1.6 and 1.6% ± 1.6%, respectively; after nCRT, these values were increased to 5.6% ± 6.1%, 3.5% ± 3.0 and 4.5% ± 2.6%, respectively (p < 0.001, p = 0.164 and p = 0.022).