Interestingly, we observed a strong downregulation of STING gene expression in both LUAD (Pval = 1.626e-07) and LUSC (Pval = 3.637e-12) (Supplementary Fig. S11F, G), suggesting that STING downregulation in SCLC and LCNEC types is even stronger in comparison to normal lung tissues. This evidence concerns the gene STING1 and small cell lung carcinoma.