We further confirm these findings by looking at specific NF-kB-driven genes (Supplementary Fig. S12A) and IRF3-dependent genes (Supplementary Fig. S12B) showing an overall downregulation of all the tested genes in SCLC, which is more significative for NF-kB-dependent genes (Supplementary Fig. S12A). The gene discussed is IRF3; the disease is small cell lung carcinoma.