ITGAE and neoplasm: Further research needs to elucidate the specific mechanism by which these cells infiltrate or differentiate in PDAC; whether the ILCs acquire the CD103+CD39+CD45RO+ phenotype locally in PDAC tissues differentiating from CD103–CD39–CD45RA+ NK cells, or whether they are already CD45RO+ but acquire markers of tumor-residence and activation (CD103/CD39) later.