SCD and cancer: Chemokines such as CCL4 have been reported to be important factors for developing a T cell-inflamed TME by recruiting DCs into tumors, which subsequently induce tumor antigen-specific CD8+ T cells and support tumor-infiltrating CD8+ effector T cells.6 In this study, we revealed two different mechanisms by which SCD1 inhibition enhances the production of CCL4 in cancer cells or CD8+ T cells.