These results indicate that in addition to enhancing CCL4 production in tumor cells, the SCD1 inhibitor also induce the high production of CCL4 by tumor infiltrating CD8+ T cells through the reduction of ER stress, suggesting that triggering of DC recruitment and subsequent T cell induction by CCL4 derived from tumor cells, and further amplification of antitumor T cell responses by CCL4 derived from tumor infiltrating CD8+ T cells. This evidence concerns the gene CCL4 and neoplasm.