SCD1 inhibition significantly enhanced the induction of tumor antigen specific CD8+ T cells in tumors and draining lymph nodes in MC38 and MCA 205 bearing mice when evaluated by the interferon (IFN)-γ secreted from tumor antigen gp70-specific T cells (figure 1D) and in CT26-bearing mice when evaluated by gp70/H-2Ld-tetramer staining (figure 1E). The gene discussed is DDX53; the disease is neoplasm.