CCL4 and malignant colon neoplasm: We then evaluated production of CCL4 by various tumor cells, including murine tumor cell lines (MC38, CT26, and 4T1), a human cancer cell lines (HT29 colon cancer and 1861mel melanoma) in vitro, and attempted to clarify the mechanisms for the inhibition of CCL4 production in tumor cells by SCD1 inhibition.