RPL35 and viral infectious disease: The HCE cell line was permissive to our HSV-1-GFP marker virus infection, and suitable for antiviral RNAi study at the viral doses used, since we observed accumulation of replication competent progeny viruses to culture supernatant (Fig 1A and 1B) and expression of the viral genes US1, UL29, and UL48 (S1 Fig) representing different regulatory gene groups.