CD274 and non-small cell lung carcinoma: Immunotherapy with anti-PD-1 (Programmed Death 1), anti-PD-L1 (Programmed Death Ligand 1) monoclonal antibodies in patients with advanced non-small cell lung cancer (NSCLC) is the most modern method, prolonging patients life with limited side effects in both monotherapy and combination therapy (De Mello et al. 2021; Qu et al. 2021).