In-depth analysis of the top 15 high-impact SNPs (Fig. S1C) also confirmed an overlap between genotypes, with only three genes with confirmed SNPs related to neurological diseases (FRG2C for bipolar disorder, and CDC27 and KIR2DL4 for white matter microstructure measurements) (Buniello et al., 2019). The gene discussed is KIR2DL4; the disease is bipolar disorder.