Then, univariate Cox analysis of the 63 intersection genes revealed that the survival of liver cirrhosis was significantly associated with 11 genes expression (P<0.05), including TIMP1, IGFBP5, ALB, HSP90AA1, CXCL2, TTR, MYC, NTRK2, CXCR4, PABPC1, and SLC29A1 (Figure 8A). The gene discussed is IGFBP5; the disease is cirrhosis of liver.