NFKB1 and colorectal carcinoma: VEGF also mediates immunosuppression in CRC by inhibiting T‐cell function, which facilitates recruitment of T‐regulatory cells (Tregs) and MDSCs, inhibits the activation and differentiation of DCs from a CD34+ precursor in the TME, and suppresses NF‐κB activation in the hematopoietic progenitor cells [128].