KRAS and colorectal carcinoma: The anomalies driving CRC oncogenesis include somatically altered genetic defects and polymorphisms that affect crucial signaling pathways, such as the Wnt, mitogen‐activated protein kinase (MAPK), Kirsten rat sarcoma viral oncogene homolog (KRAS), transforming growth factor beta (TGF‐β)/bone morphogenetic protein, and DNA damage response pathways [13, 14, 15].