A large number of experiments have proved that YY1 was highly expressed in many tumors, including breast cancer [31], prostate cancer [32], colon cancer [33], ovarian cancer [34], esophageal cancer [35], nervous system tumors [36], pancreatic cancer [37], osteosarcoma [38], and melanoma [39]. This evidence concerns the gene YY1 and familial pancreatic carcinoma.