When comparing the differentially expressed proteins in samples from MS patients and HCs identified in the iteration analyses, we discovered that diphthamide synthetase, encoded by DPH6 ̧ was found in 98 iterations of the unstimulated samples, while Grb2-related adapter protein and enhancer of polycomb homolog, encoded by GRAP and EPC1, respectively, were found in all 100 iterations from stimulated samples. Here, EPC1 is linked to myeloid sarcoma.