We identified enrichment in ten biological processes (Fig. 4A; − log(B-H p-value) > 1.3) among the proteins exclusively changed upon stimulation of CD4+ T cells from MS patients, whereas among the proteins exclusively changed upon activation of CD4+ T cells from HCs, we identified one biological process (Fig. 4B; − log(B-H p-value) > 1.3). Here, CD4 is linked to myeloid sarcoma.