When comparing protein abundances in the T cell samples from HCs and MS patients, 18 and 33 proteins were differentially expressed (adjusted p ≤ 0.05) in unstimulated (Table 2, Fig. 1C) and stimulated CD4+ T cells (Table 3, Fig. 1D), respectively, with two proteins; diphthamide synthetase, encoded by DPH6, and enhancer of polycomb homolog 1, encoded by EPC1, being significant in both conditions. Here, DPH6 is linked to myeloid sarcoma.