However, compared to Jung’s study, our model showed 9 indicators including night sweat, perianal fistula, intestinal obstruction, intestinal surgery, elevated PLT, elevated CRP, T-SPOT positive, transverse ulcer, involvement of jejunum were the vital markers to differentiate the two diseases,with a sensitivity, specificity of 78.4%, 89.9%, respectively. This evidence concerns the gene CRP and intestinal obstruction.