To investigate the roles of PKM2 and TRIB2 in regulating lung cancer cell growth in vivo, lentiviral vectors were then constructed as a previous report [28] to stably express PKM2, shPKM2, TRIB2, shTRIB2, or controls to further investigate the effect of PKM2 or TRIB2 on cancer cell proliferation in xenografts. This evidence concerns the gene PKM and lung carcinoma.