BCL2L11 and endometrial cancer: Therefore, we believe that SNORD89 may be involved in the progression of endometrial cancer by regulating Bim. In order to verify that SNORD89 plays its carcinogenic role through 2′-O-methylation modification of Bim mRNA, we designed corresponding primers and detected whether there was 2′-O-methylation modification at SNORD89 and Bim pairing site by the RTL-P method.