This was supported by earlier transcriptome data, 20% of the genes were involved in ROS turnover during PPD process (Reilly et al., 2007), and overexpression of superoxide dismutase (SOD) and catalase (CAT) would delayed PPD occurrence of cassava tuberous roots (Xu et al., 2013). The gene discussed is SOD1; the disease is progressive pseudorheumatoid arthropathy of childhood.