CD4 and metabolic dysfunction-associated steatohepatitis: In response to inflammatory stimuli, CD4+ T cells can also differentiate into helper T cells type 17 (TH17), the accumulation of which was found to be associated with progression from NAFLD to NASH, and interestingly, these changes appear to go back to normality at 1 year after bariatric surgery, along with improvements in liver inflammation [46, 48, 63–65].