Finally, the hub genes determined by the aforementioned three means are visualized as a Venn graph, as shown in Figure 5(a), including SRGN, CD53, EVI2B, MPEG1, NCKAP1L, LCP1, and TYROBP. We utilized Attie Lab Diabetes Database to validate the mRNA levels of the above-mentioned genes in obese mice, except SRGN which was lacking in the database (Figure 5(b)). The gene discussed is CD53; the disease is diabetes mellitus.