MKI67 and neoplasm: Additionally, when compared with those of the sham group, the expression levels of Ki67 in the tumor tissues of the 3 UBE treatment groups and UBE + PEM group were significantly decreased (P < 0.05) and the expression levels of Ki67 in tumor tissues of the UBE + PEM group were considerably lower than those of the 15 mg/ml UBE group (P < 0.05) (Figure 6(e)).