Additionally, we found transcriptional regulators that are either activated (IRF3, STAT1, IRF7, MXD1) or inhibited (MLXIPL, MYC, TRIM24, TP53, SIRT1, HSF1, MYCL, GLIS2, CEBPB, NFE2L2) in BECs following infection (Table 6). The gene discussed is HSF1; the disease is infection.