In particular, ACTL6A, CHD2, and ACTB were identified with amplified events in at least five cancer types, whereas CHD5, INO80, SHPRH, ACTR8, HELLS, RAD54L2, BTAF1, SMARCAL1 and CHD3 were found with deleted events in at least five cancer types (Figure 1A and Table S3). Here, ACTB is linked to cancer.