CD8A and vitiligo: Tissue-resident fibroblasts are known to play a role in scar fibrosis [134, 135], and have emerged as a key cell type in regulating the activation or suppression of the immune response [136], For example, dermal fibroblasts that recruit and activate CD8+ cytotoxic T cells through secreted chemokines are responsible for driving patterned autoimmune activity in vitiligo [137].