The top 10 pathways were insulin secretion; apoptosis; adrenergic signaling in cardiomyocytes; cell adhesion molecules (CAMs); JAK-STAT signaling pathway; transcriptional mis-regulation in cancer; arginine biosynthesis; maturity-onset diabetes of the young; ascorbate and aldarate metabolism; and fatty acid elongation. The gene discussed is SOAT1; the disease is cancer.