GPER1 and autism spectrum disorder: In addition, emerging research suggests that GPER may contribute to the etiology of neurodevelopmental and neuropsychiatric disorders, including autism spectrum disorder (Altun et al., 2017), schizophrenia (Gogos et al., 2015), attention deficit hyperactivity disorder (Sahin et al., 2018), anxiety (Li et al., 2013; Tian et al., 2013), and depression (McAllister et al., 2012, 2014).