Overall, five cancer (sub)types exhibited elevated iron uptake levels, including BRCA_TNBC (P = 0.043), colon adenocarcinoma (COAD; P = 2E−16), kidney renal clear cell carcinoma (KIRC; P = 0.02), lung adenocarcinoma (LUAD; P = 1E−10), and STAD (P = 1E−7); three showed reduced iron uptake levels, namely HNSC (P = 0.02), kidney renal papillary cell carcinoma (KIRP; P = 1E−5), and THCA (P = 3E−15); and three had approximately the same levels: BRCA_Luminal, BRCA_HER2, and prostate adenocarcinoma (PRAD). The gene discussed is ERBB2; the disease is cancer.