IL3000-infected mice had increased numbers of extravascular B cells in the brain parenchyma (two-way ANOVA, p-value = 0.0341), whereas in the 1/148 infection, T helper cells (CD4+) were increased by twofold (two-way ANOVA, p-value = 0.0.0305; Figure 4I). The gene discussed is CD4; the disease is infection.