We paid attention to FKBP5 because of its function as an androgen receptor gene, our study showed FKBP5 gene polymorphisms are associated with PCOS generally (rs1360780, rs3800373) and with the hyperandrogenism subtype specifically (rs1360780, rs9470080, rs9296158, rs1043805, rs7757037), among which rs3800373 and rs1043805 belong to 3’ UTR variant of FKBP5 gene. This evidence concerns the gene AR and polycystic ovary syndrome.