Several of the most highly induced genes, CHI3L1, GPX1, PLIN1, PLIN4, and JAK3, have been linked to enhanced growth or cell survival in other tumor types (Cheng et al., 2019; Qiu et al., 2018; Sirois et al., 2019; Vadivel et al., 2021; Zhang et al., 2020). The gene discussed is PLIN4; the disease is neoplasm.