FOS and cardiac arrhythmia: This was probably related to the acupoint specificity of the Neiguan point, which was found to affect the firing frequency of the amygdala and regulate autonomic balance [34], as well as to reduce the expression of c-fos cells in the nucleus tractus solitarius, thereby counteracting the activation of neurons in the nucleus tractus solitarius by afferent information brought on by arrhythmias and reducing heart rate [35].