These results suggested that METTL3 may be associated with the proliferation of dysplastic cells in esophageal SCC and OSCC.17, 24In agreement with previous studies,14, 15, 16, 17, 18it was found that METTL3 was overexpressed in OSCC when compared with NOM. Here, METTL3 is linked to esophageal squamous cell carcinoma.