Moreover, IL‐6 signaling blockade prevented IL‐17 IL‐22, CCL20, and CCR6 upregulation, and the infiltration of CD3+ T cells to degenerating hair follicles, and, vis‐a‐versa; IR‐induced IL‐6 upregulation was strongly dependent upon IL‐17 upregulation, CCR6‐dependent immune cell infiltration upon loss of HF immune privilege. The gene discussed is IL17A; the disease is hydrops fetalis.