CDKN2A and psoriasis: In this and other respects, IRIAD shows a high degree of similarity with psoriasis, including the Th17 cytokine‐related inflammatory response, as well as the simultaneous presence of keratinocyte hyperplasia together with the presence of cellular senescence in keratinocytes associated with high IGFBP2 expression and p16INK4a upregulation (Mercurio et al, 2020).