Similar to TN-C, TN-W was often found to be expressed in close proximity to the vasculature as assessed by co-staining of TN-W with endothelial cell markers CD31/Pecam-1, von-Willebrand-factor, and Desmin in at least kidney, lung, breast, colon, ovary, and brain cancers (48, 90). Here, TNC is linked to brain cancer.