GO functional enrichment analysis (Figure 2(a)) showed that DEGs were enriched in neutrophil degranulation, neutrophil activation involved in immune response, collagen-containing extracellular matrix, primary lysosome, and vesicle lumen; KEGG pathway analysis (Figure 2(b)) showed that the DEGs were concentrated in the HIF-1 signaling pathway, PI3K-AKT signaling pathway, and cell cycle, whereas DO enrichment analysis (Figure 2(c)) showed that DEGs were significantly expressed in cardiovascular diseases, periodontal disease, and OA. This evidence concerns the gene AKT1 and cardiovascular disorder.