CD4 and neoplasm: However, for Hepa 1-6 tumor model, treatment with 100 mg/kg ART could decrease the percentages of MDSCs, G-MDSCs, and Treg cells but increased the percentages of CD3+, CD4+, and CD8+ T cells, while there was no change in the percentages of M-MDSCs compared to treatment with DMSO (Figs. S4G-H and S4J-L).