CD4 and neoplasm: For B16F10 tumor model, treatment with 100 mg/kg ART significantly decreased the percentages of MDSCs, M-MDSCs, and G-MDSCs but increased the percentages of CD3+ and CD8+ T cells, while there was no change in the percentages of CD4+ T cells and Treg cells compared to treatment with DMSO (Figures 4(e), 4(f), and 4(h)–4(j)).