FUS and amyotrophic lateral sclerosis: RBP-encoding transcripts as well as genetic mutations in RBPs have been shown to be associated with NDs, including ALS and FTD, where mutations in TARDP, FUS, ATXN2, MATR3, TIA-1, HNRNPA1, and HNRNPA2B1 occur (Sreedharan et al., 2008; Kwiatkowski et al., 2009; Kim et al., 2013a; Johnson et al., 2014; Conlon and Manley, 2017; Kapeli et al., 2017; Mackenzie et al., 2017; Abramzon et al., 2020).