Additionally, in silico analyses of these signatures revealed that FGFR3, has-miR-486-5p, and lnc-KCNH5-1 and pathways associated with Cytokine-cytokine receptor interaction, Oxidative phosphorylation, and Parkinson’s disease may play a vital role in developing TLE+HS. This evidence concerns the gene FGFR3 and Parkinson disease.