DNMT3A and non-small cell lung carcinoma: In non-small-cell lung cancer (NSCLC), METTL3 promotes the translation of mRNAs of certain genes by increasing m6A levels, including c-Myc, BCL-2, epidermal growth factor receptor (EGFR), hippo pathway effector TAZ and YAP, MAPKAPK2 (MK2), and DNMT3A, thereby promoting lung adenocarcinoma (LUAD) cell proliferation, survival, invasion and metastasis (Lin et al., 2016; Jin et al., 2019; Wu et al., 2021a; Zhang et al., 2021c).