Baicalin can reduce the m6A modification level of HKDC mRNA by inhibiting METTL3, which leads to the decrease of HKDC expression and the upregulation of HKDC/JAK2/STAT1/caspase-3 signaling pathway, and finally inhibits the invasion and metastasis of tumor cells (Jiang et al., 2022). Here, CASP3 is linked to neoplasm.