NOTCH1 and gastric cancer: The attenuated angiogenesis mediated by Xiaotan Sanjie decoction that comprised eleven herbs (including Pinelliae rhizome, Rhizoma arisaematis, and Poria cocos) in gastric cancer was related to the Notch-1/VEGF and IL-8/VEGF/VEGFR signaling axis (Yan et al., 2014; Shi et al., 2016).