We found that cisplatin-pretreated tumor cells stimulate neutrophils which expressed higher levels of cytotoxic effectors, including TNF-α, GZMB, and ELANE (Figure 3D), and pro-inflammatory cytokines, such as CCL2, CCL3, CXCL10, CXCL11, and IL12 (Figure 3E). This evidence concerns the gene ELANE and neoplasm.