TACR1 and cancer: Recently, it has been reported that the NK-1 receptor (NK1R) played a pivotal in the development of cancer, including pancreatic cancer, thyroid cancer, gastrointestinal cancer and breast carcinoma (Muñoz and Coveñas, 2014; Muñoz and Coveñas, 2016; Ebrahimi et al., 2020; Isorna et al., 2020).