Some studies found that urinary NGAL can be used to distinguish ATN from PRA and HRS, and it is also an independent predictor of poor prognosis in patients with liver cirrhosis (Barreto et al., 2014; Belcher et al., 2014; Puthumana et al., 2017; Hamdy et al., 2018; Jaques et al., 2019),and a study found that urinary NGAL can be used to distinguish PRA from ATN in patients without cirrhosis (Nickolas et al., 2008). The gene discussed is LCN2; the disease is cirrhosis of liver.