Expression of HIF-1α in the CA-AKI + Fasudil (vs. CA-AKI) group was significantly reduced at all time points (Day 1, p < 0.0001; Day 3, p = 0.008; Day 7, p = 0.004; Day 13, p < 0.0001) (Figure 9D). This evidence concerns the gene HIF1A and acute kidney injury.