ROCK1 and acute kidney injury: There was also a progressive decline of ROCK-1 expression in the CA-AKI + Fasudil (vs. CA-AKI) group following iopromide injection (Days 1–13) (Day 1, p < 0.0001; Day 3, p < 0.0001; Day 7, p < 0.0001; Day 13, p < 0.0001), as shown by immunostain (Figures 8C,D).