BMP2 and focal segmental glomerulosclerosis: The protein expression of BMP2 was up-regulated in the kidney tissues of ADR-induced FSGS model, while the YSHS granule significantly decreased the expression of BMP2 in the ADR-induced FSGS model (Figures 6A,B), which was consistent with the expression trend of Bmp2 mRNA detected by Real-time PCR (Figure 5A).