Results showed that the YSHS granule down-regulated the expressions of Bmp2, Gsta1, Gsta3, Bst1, and S100a9 (Figure 5A), and up-regulated the expressions of Ttr and Gatm (Figure 5B) in the kidney tissues of ADR-induced FSGS model mice, while there were no significant changes on the expressions of Igf1, Ren, Pck1, Alb, Pah, Ctsv, Dcxr, and Tnnc1. This evidence concerns the gene PCK1 and focal segmental glomerulosclerosis.