Mutations associated with SIOD and CSS4 impairs the co-localization: Mutations in SMARCAL1 cause Schmike Immuno‐osseous Dysplasia (SIOD) while mutations in BRG1 are associated with Coffin-Siris Syndrome (CSS4) (Boerkoel et al., 2002; Tsurusaki et al., 2012). This evidence concerns the gene SMARCA4 and Schimke immuno-osseous dysplasia.