MIR205HG and cancer: Understanding the mechanism of action of MIR205HG/LEADR will allow to dissect the processes governing differentiation of epithelial cells, which often appear deregulated in cancer (Ferrari and Gandellini, 2020), and eventually lay the foundations for the development of novel therapeutic approaches for tumors where MIR205HG/LEADR expression is deregulated (Di Agostino et al., 2018; Li et al., 2019; Liu et al., 2020; Song et al., 2021; Dong et al., 2022).